Projects
EPS secretion
EPS secretion
We combine cryo-EM, X-ray crystallography, imaging, biophysical and biochemical assays, molecular biology and classical bacteriology to study the structural determinants of exopolysaccharide secretion in bacterial biofilms.
c-di-GMP signaling
c-di-GMP signaling
We are interested in the mechanisms of c-di-GMP signal transduction and its inverse effects on flagellar motility and biofilm formation.
ARTICLES :
Krasteva @ & Sondermann @, Nature Chemical Biology 2017
Matsuyama*, Krasteva* et al., PNAS 2016